Long-Term Potentiation of Excitatory Synaptic Strength in Spinothalamic Tract Neurons of the Rat Spinal Cord
نویسندگان
چکیده
منابع مشابه
Long-Term Potentiation of Excitatory Synaptic Strength in Spinothalamic Tract Neurons of the Rat Spinal Cord
Spinal dorsal horn nociceptive neurons have been shown to undergo long-term synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). Here, we focused on the spinothalamic tract (STT) neurons that are the main nociceptive neurons projecting from the spinal cord to the thalamus. Optical technique using fluorescent dye has made it possible to identify the STT neu...
متن کاملLong-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord.
Synaptic transmission between dorsal root afferents and neurons in the superficial laminae of the spinal dorsal horn (laminae I-III) was examined by intracellular recording in a transverse slice preparation of rat spinal cord. Brief high-frequency electrical stimulation (300 pulses at 100 Hz) of primary afferent fibers produced a long-term potentiation (LTP) or a long-term depression (LTD) of f...
متن کاملAlternative Medicine in Neuropathic Pain Opioids in the Spinal Cord and Central Sensitization Spinothalamic Tract Neurons, Role of Nitric Oxide Long-Term Potentiation and Long-Term Depression in the Spinal Cord
This is a long-lasting increase in synaptic efficacy resulting from repetitive activation of the synapse. This process was first described in hippocampus, whereby high-frequency stimulation of afferent pathways leads to a potentiated post-synaptic response that can last for hours to days. It is a form of activity-dependent plasticity. LTPmay increase the efficiencyof pain transmission for weeks...
متن کاملLong-term potentiation of pain "memory" in the spinal cord.
1. Marsden JF, Limousin-Dowsey P, Ashby P, Pollak P, Brown P. Subthalamic nucleus, sensorimotor cortex and muscle interrelationships in Parkinson’s disease. Brain. 2001;124(pt 2):378-388. 2. de Hemptinne C, Ryapolova-Webb ES, Air EL, et al. Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease. Proc Natl Acad Sci U S A. 2013;110(12):4780-4785. 3. Herz DM, Florin ...
متن کاملthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Korean Journal of Physiology & Pharmacology
سال: 2013
ISSN: 1226-4512,2093-3827
DOI: 10.4196/kjpp.2013.17.6.553